ParkinsonCanadaV1, Main, Exploration, bibRecord, 004A88

Positron emission tomography in manganese intoxication

Identifieur interne : 004A88 ( Main/Exploration ); précédent : 004A87; suivant : 004A89

Positron emission tomography in manganese intoxication

Auteurs : E. Ch Wolters [République populaire de Chine] ; C. Huang [République populaire de Chine] ; C. Clark [République populaire de Chine] ; R. F. Peppard [République populaire de Chine] ; J. Okada [République populaire de Chine] ; N. Chu [République populaire de Chine] ; M. J. Adam [Canada] ; T. J. Ruth [Canada] ; D. Li [République populaire de Chine] ; D. Calne [République populaire de Chine, Canada]

Source :

Annals of Neurology [ 0364-5134 ] ; 1989-11.

RBID : ISTEX:07CE847F3C9720A2626A33C335E20D8764A996CD

Descripteurs français

Pascal (Inist)
- Exposition professionnelle, Glucose, Homme, Manganèse, Métabolisme, Parkinson maladie, Radiodiagnostic, Système nerveux pathologie, Tomoscintigraphie, Toxicité, Transmission dopaminergique, Voie nigrostriatale.
Wicri :
- topic : Glucose, Homme, Manganèse.

English descriptors

KwdEn :
- Adult, Brain (metabolism), Brain (pathology), Chronic Disease, Dihydroxyphenylalanine (analogs & derivatives), Dihydroxyphenylalanine (pharmacokinetics), Dopaminergic transmission, Glucose, Human, Humans, Magnetic Resonance Imaging, Manganese, Manganese Poisoning, Metabolism, Nervous system diseases, Nigrostriatal pathway, Occupational exposure, Parkinson Disease, Secondary (chemically induced), Parkinson Disease, Secondary (diagnosis), Parkinson Disease, Secondary (diagnostic imaging), Parkinson disease, Positron emission tomography, Radiodiagnosis, Tomography, Emission-Computed, Toxicity.
MESH :
- chemical , analogs & derivatives : Dihydroxyphenylalanine.
- chemically induced : Parkinson Disease, Secondary.
- diagnosis : Parkinson Disease, Secondary.
- diagnostic imaging : Parkinson Disease, Secondary.
- metabolism : Brain.
- pathology : Brain.
- chemical , pharmacokinetics : Dihydroxyphenylalanine.
- Adult, Chronic Disease, Humans, Magnetic Resonance Imaging, Manganese Poisoning, Tomography, Emission-Computed.

Abstract

We employed 6‐fluorodopa to study the integrity of the nigrostriatal dopaminergic projection by positron emission tomography in 4 subjects with clinical features of mild parkinsonism caused by exposure to manganese. The 6‐fluorodopa scans were normal. This finding suggests that in early manganism sufficient to cause parkinsonian deficits, damage may occur in pathways postsynaptic to the nigrostriatal system, probably involving striatal or pallidal neurons. Fluorodeoxyglucose scans showed decreased cortical glucose metabolism, the significance of which is discussed.

Url:

https://api-v5.istex.fr/document/07CE847F3C9720A2626A33C335E20D8764A996CD/fulltext/pdf

DOI: 10.1002/ana.410260510

Affiliations:

Canada, République populaire de Chine

Le document en format XML

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<front><div type="abstract" xml:lang="en">We employed 6‐fluorodopa to study the integrity of the nigrostriatal dopaminergic projection by positron emission tomography in 4 subjects with clinical features of mild parkinsonism caused by exposure to manganese. The 6‐fluorodopa scans were normal. This finding suggests that in early manganism sufficient to cause parkinsonian deficits, damage may occur in pathways postsynaptic to the nigrostriatal system, probably involving striatal or pallidal neurons. Fluorodeoxyglucose scans showed decreased cortical glucose metabolism, the significance of which is discussed.</div>
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La maladie de Parkinson au Canada (serveur d'exploration)

Positron emission tomography in manganese intoxication

Positron emission tomography in manganese intoxication

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	La maladie de Parkinson au Canada (serveur d'exploration)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.